Precision medicine: an approach to R&D for delivering superior medicines to patients

Pharmaceutical R&D productivity has declined over the last decade despite increasing investments. Recent trends, however, indicate a potential reversal of this trend fueled by a wave of new biologics, vaccines and highly selective NCEs directed against targets validated by human genetics, focus...

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Detalles Bibliográficos
Autores principales: Dolsten, Mikael, Søgaard, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567426/
https://www.ncbi.nlm.nih.gov/pubmed/23369459
http://dx.doi.org/10.1186/2001-1326-1-7
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author Dolsten, Mikael
Søgaard, Morten
author_facet Dolsten, Mikael
Søgaard, Morten
author_sort Dolsten, Mikael
collection PubMed
description Pharmaceutical R&D productivity has declined over the last decade despite increasing investments. Recent trends, however, indicate a potential reversal of this trend fueled by a wave of new biologics, vaccines and highly selective NCEs directed against targets validated by human genetics, focus on new disease areas including orphan and genetic diseases and more precise tailoring of medicines to their target populations.
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spelling pubmed-35674262013-02-08 Precision medicine: an approach to R&D for delivering superior medicines to patients Dolsten, Mikael Søgaard, Morten Clin Transl Med Editorial Pharmaceutical R&D productivity has declined over the last decade despite increasing investments. Recent trends, however, indicate a potential reversal of this trend fueled by a wave of new biologics, vaccines and highly selective NCEs directed against targets validated by human genetics, focus on new disease areas including orphan and genetic diseases and more precise tailoring of medicines to their target populations. Springer 2012-05-30 /pmc/articles/PMC3567426/ /pubmed/23369459 http://dx.doi.org/10.1186/2001-1326-1-7 Text en Copyright ©2012 Dolsten and Sogaard; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Editorial
Dolsten, Mikael
Søgaard, Morten
Precision medicine: an approach to R&D for delivering superior medicines to patients
title Precision medicine: an approach to R&D for delivering superior medicines to patients
title_full Precision medicine: an approach to R&D for delivering superior medicines to patients
title_fullStr Precision medicine: an approach to R&D for delivering superior medicines to patients
title_full_unstemmed Precision medicine: an approach to R&D for delivering superior medicines to patients
title_short Precision medicine: an approach to R&D for delivering superior medicines to patients
title_sort precision medicine: an approach to r&d for delivering superior medicines to patients
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567426/
https://www.ncbi.nlm.nih.gov/pubmed/23369459
http://dx.doi.org/10.1186/2001-1326-1-7
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