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Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

BACKGROUND: Cis-Platinum (II) (cis-diammine dichloroplatinum; CDDP) is a potent antitumor compound widely used for the treatment of many malignancies. An important side-effect of CDDP is nephrotoxicity. The cytotoxic action of this drug is often thought to induce oxidative stress and be associated w...

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Detalles Bibliográficos
Autores principales:	Brahmi, Dalel, Ayed, Yousra, Hfaiedh, Mbarka, Bouaziz, Chayma, Mansour, Hedi Ben, Zourgui, Lazhar, Bacha, Hassen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567432/ https://www.ncbi.nlm.nih.gov/pubmed/22849573 http://dx.doi.org/10.1186/1472-6882-12-111

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