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An evolutionary explanation for the presence of cancer nonstem cells in neoplasms

Contrary to conventional views that assume all cells in a neoplasm can propagate the tumor, the cancer stem cell hypothesis posits that only a fraction of the cells (the cancer stem cells) can act as tumor-propagating cells, while most of the tumor is composed of cells with limited replication poten...

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Detalles Bibliográficos
Autores principales: Sprouffske, Kathleen, Athena Aktipis, C, Radich, Jerald P, Carroll, Martin, Nedelcu, Aurora M, Maley, Carlo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567474/
https://www.ncbi.nlm.nih.gov/pubmed/23397439
http://dx.doi.org/10.1111/eva.12030

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