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An evolutionary explanation for the presence of cancer nonstem cells in neoplasms
Contrary to conventional views that assume all cells in a neoplasm can propagate the tumor, the cancer stem cell hypothesis posits that only a fraction of the cells (the cancer stem cells) can act as tumor-propagating cells, while most of the tumor is composed of cells with limited replication poten...
Autores principales: | Sprouffske, Kathleen, Athena Aktipis, C, Radich, Jerald P, Carroll, Martin, Nedelcu, Aurora M, Maley, Carlo C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567474/ https://www.ncbi.nlm.nih.gov/pubmed/23397439 http://dx.doi.org/10.1111/eva.12030 |
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