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SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence

AIMS: Although endothelial cell senescence is known to play an important role in the development of cardiovascular pathologies, mechanisms that attenuate this process have not been extensively investigated. The aim of this study was to investigate whether SIRT6, a member of the sirtuin family of NAD...

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Detalles Bibliográficos
Autores principales: Cardus, Anna, Uryga, Anna K., Walters, Gareth, Erusalimsky, Jorge D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567786/
https://www.ncbi.nlm.nih.gov/pubmed/23201774
http://dx.doi.org/10.1093/cvr/cvs352

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