Optimizing patient derived mesenchymal stem cells as virus carriers for a Phase I clinical trial in ovarian cancer

BACKGROUND: Mesenchymal stem cells (MSC) can serve as carriers to deliver oncolytic measles virus (MV) to ovarian tumors. In preparation for a clinical trial to use MSC as MV carriers, we obtained cells from ovarian cancer patients and evaluated feasibility and safety of this approach. METHODS: MSC...

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Detalles Bibliográficos
Autores principales: Mader, Emily K, Butler, Greg, Dowdy, Sean C, Mariani, Andrea, Knutson, Keith L, Federspiel, Mark J, Russell, Stephen J, Galanis, Evanthia, Dietz, Allan B, Peng, Kah-Whye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567956/
https://www.ncbi.nlm.nih.gov/pubmed/23347343
http://dx.doi.org/10.1186/1479-5876-11-20

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