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ROCS: a Reproducibility Index and Confidence Score for Interaction Proteomics Studies
BACKGROUND: Affinity-Purification Mass-Spectrometry (AP-MS) provides a powerful means of identifying protein complexes and interactions. Several important challenges exist in interpreting the results of AP-MS experiments. First, the reproducibility of AP-MS experimental replicates can be low, due bo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568013/ https://www.ncbi.nlm.nih.gov/pubmed/22682516 http://dx.doi.org/10.1186/1471-2105-13-128 |