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Isoflurane Increases Neuronal Cell Death Vulnerability by Downregulating miR-214

Since accumulating evidence suggests the application of anesthetics may increase the risk of Alzheimer’s disease (AD), we investigated the cytotoxicity of inhaled general anesthesia in neurons and its underlying mechanism. Using primary cultured rat hippocampal neurons as the study model, here we sh...

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Detalles Bibliográficos
Autores principales: Yan, Hailiang, Xu, Tao, Zhao, Hongfeng, Lee, Kuo-Chieh, Wang, Hoau-Yan, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568119/
https://www.ncbi.nlm.nih.gov/pubmed/23408966
http://dx.doi.org/10.1371/journal.pone.0055276