Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic Mice

Amyloid precursor protein (APP) proteolysis is required for production of amyloid-β (Aβ) peptides that comprise β-amyloid plaques in brains of Alzheimer’s disease (AD) patients. Recent AD therapeutic interest has been directed toward a group of anti-amyloidogenic compounds extracted from plants. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Mori, Takashi, Koyama, Naoki, Guillot-Sestier, Marie-Victoire, Tan, Jun, Town, Terrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568151/
https://www.ncbi.nlm.nih.gov/pubmed/23409038
http://dx.doi.org/10.1371/journal.pone.0055774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568151/
https://www.ncbi.nlm.nih.gov/pubmed/23409038
http://dx.doi.org/10.1371/journal.pone.0055774

Ejemplares similares