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rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention

Sustained attention is an essential brain function that enables a subject to maintain attention level over the time of a task. In previous work, the right inferior parietal lobe (IPL) has been reported as one of the main brain regions related to sustained attention, however, the right lateralization...

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Autores principales: Lee, Jeyeon, Ku, Jeonghun, Han, Kiwan, Park, Jinsick, Lee, Hyeongrae, Kim, Kyung Ran, Lee, Eun, Husain, Masud, Yoon, Kang Jun, Kim, In Young, Jang, Dong Pyo, Kim, Sun I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568694/
https://www.ncbi.nlm.nih.gov/pubmed/23403477
http://dx.doi.org/10.3389/fnhum.2013.00026
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author Lee, Jeyeon
Ku, Jeonghun
Han, Kiwan
Park, Jinsick
Lee, Hyeongrae
Kim, Kyung Ran
Lee, Eun
Husain, Masud
Yoon, Kang Jun
Kim, In Young
Jang, Dong Pyo
Kim, Sun I.
author_facet Lee, Jeyeon
Ku, Jeonghun
Han, Kiwan
Park, Jinsick
Lee, Hyeongrae
Kim, Kyung Ran
Lee, Eun
Husain, Masud
Yoon, Kang Jun
Kim, In Young
Jang, Dong Pyo
Kim, Sun I.
author_sort Lee, Jeyeon
collection PubMed
description Sustained attention is an essential brain function that enables a subject to maintain attention level over the time of a task. In previous work, the right inferior parietal lobe (IPL) has been reported as one of the main brain regions related to sustained attention, however, the right lateralization of vigilance/sustained attention is unclear because information about the network for sustained attention is traditionally provided by neglect patients who typically have right brain damage. Here, we investigated sustained attention by applying a virtual lesion technique, transcranial magnetic stimulation (TMS), over the left and right superior parietal lobe (SPL) and IPL. We used two different types of visual sustained attention tasks: spatial (location based) and non-spatial (feature based). When the participants performed the spatial task, repetitive TMS (rTMS) over either the right or left IPL induced a significant decrement of sustained attention causing a progressive increment of errors and response time. In contrast, participants' performance was not changed by rTMS on the non-spatial task. Also, omission errors (true negative) gradually increased with time on right and left IPL rTMS conditions, while commission errors (false positive) were relatively stable. These findings suggest that the maintenance of attention, especially in tasks regarding spatial location, is not uniquely lateralized to the right IPL, but may also involve participation of the left IPL.
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spelling pubmed-35686942013-02-12 rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention Lee, Jeyeon Ku, Jeonghun Han, Kiwan Park, Jinsick Lee, Hyeongrae Kim, Kyung Ran Lee, Eun Husain, Masud Yoon, Kang Jun Kim, In Young Jang, Dong Pyo Kim, Sun I. Front Hum Neurosci Neuroscience Sustained attention is an essential brain function that enables a subject to maintain attention level over the time of a task. In previous work, the right inferior parietal lobe (IPL) has been reported as one of the main brain regions related to sustained attention, however, the right lateralization of vigilance/sustained attention is unclear because information about the network for sustained attention is traditionally provided by neglect patients who typically have right brain damage. Here, we investigated sustained attention by applying a virtual lesion technique, transcranial magnetic stimulation (TMS), over the left and right superior parietal lobe (SPL) and IPL. We used two different types of visual sustained attention tasks: spatial (location based) and non-spatial (feature based). When the participants performed the spatial task, repetitive TMS (rTMS) over either the right or left IPL induced a significant decrement of sustained attention causing a progressive increment of errors and response time. In contrast, participants' performance was not changed by rTMS on the non-spatial task. Also, omission errors (true negative) gradually increased with time on right and left IPL rTMS conditions, while commission errors (false positive) were relatively stable. These findings suggest that the maintenance of attention, especially in tasks regarding spatial location, is not uniquely lateralized to the right IPL, but may also involve participation of the left IPL. Frontiers Media S.A. 2013-02-11 /pmc/articles/PMC3568694/ /pubmed/23403477 http://dx.doi.org/10.3389/fnhum.2013.00026 Text en Copyright © 2013 Lee, Ku, Han, Park, Lee, Kim, Lee, Husain, Yoon, Kim, Jang and Kim. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Neuroscience
Lee, Jeyeon
Ku, Jeonghun
Han, Kiwan
Park, Jinsick
Lee, Hyeongrae
Kim, Kyung Ran
Lee, Eun
Husain, Masud
Yoon, Kang Jun
Kim, In Young
Jang, Dong Pyo
Kim, Sun I.
rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention
title rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention
title_full rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention
title_fullStr rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention
title_full_unstemmed rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention
title_short rTMS over bilateral inferior parietal cortex induces decrement of spatial sustained attention
title_sort rtms over bilateral inferior parietal cortex induces decrement of spatial sustained attention
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568694/
https://www.ncbi.nlm.nih.gov/pubmed/23403477
http://dx.doi.org/10.3389/fnhum.2013.00026
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