Personalized medicine and atrial fibrillation: will it ever happen?

Atrial fibrillation (AF) is a common arrhythmia of substantial public health importance. Recent evidence demonstrates a heritable component underlying AF, and genetic discoveries have identified common variants associated with the arrhythmia. Ultimately one hopes that the consideration of genetic va...

Descripción completa

Detalles Bibliográficos
Autores principales: Lubitz, Steven A, Ellinor, Patrick T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568716/
https://www.ncbi.nlm.nih.gov/pubmed/23210687
http://dx.doi.org/10.1186/1741-7015-10-155
Descripción
Sumario:Atrial fibrillation (AF) is a common arrhythmia of substantial public health importance. Recent evidence demonstrates a heritable component underlying AF, and genetic discoveries have identified common variants associated with the arrhythmia. Ultimately one hopes that the consideration of genetic variation in clinical practice may enhance care and improve health outcomes. In this review we explore areas of potential clinical utility in AF management including those relating to pharmacogenetics and risk prediction.

Ejemplares similares