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Array-A-Lizer: A serial DNA microarray quality analyzer

BACKGROUND: The proliferate nature of DNA microarray results have made it necessary to implement a uniform and quick quality control of experimental results to ensure the consistency of data across multiple experiments prior to actual data analysis. RESULTS: Array-A-Lizer is a small and convenient s...

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Detalles Bibliográficos
Autores principales: Petri, Andreas, Fleckner, Jan, Matthiessen, Mads Wichmann
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC356907/
https://www.ncbi.nlm.nih.gov/pubmed/15018654
http://dx.doi.org/10.1186/1471-2105-5-12
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author Petri, Andreas
Fleckner, Jan
Matthiessen, Mads Wichmann
author_facet Petri, Andreas
Fleckner, Jan
Matthiessen, Mads Wichmann
author_sort Petri, Andreas
collection PubMed
description BACKGROUND: The proliferate nature of DNA microarray results have made it necessary to implement a uniform and quick quality control of experimental results to ensure the consistency of data across multiple experiments prior to actual data analysis. RESULTS: Array-A-Lizer is a small and convenient stand-alone tool providing the necessary initial analysis of hybridization quality of an unlimited number of microarray experiments. The experiments are analyzed for even hybridization across the slide and between fluorescent dyes in two-color experiments in spotted DNA microarrays. CONCLUSIONS: Array-A-Lizer allows the expedient determination of the quality of multiple DNA microarray experiments allowing for a rapid initial screening of results before progressing to further data analysis. Array-A-Lizer is directed towards speed and ease-of-use allowing both the expert and non-expert microarray researcher to rapidly assess the quality of multiple microarray hybridizations. Array-A-Lizer is available from the Internet as both source code and as a binary installation package.
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spelling pubmed-3569072004-03-05 Array-A-Lizer: A serial DNA microarray quality analyzer Petri, Andreas Fleckner, Jan Matthiessen, Mads Wichmann BMC Bioinformatics Software BACKGROUND: The proliferate nature of DNA microarray results have made it necessary to implement a uniform and quick quality control of experimental results to ensure the consistency of data across multiple experiments prior to actual data analysis. RESULTS: Array-A-Lizer is a small and convenient stand-alone tool providing the necessary initial analysis of hybridization quality of an unlimited number of microarray experiments. The experiments are analyzed for even hybridization across the slide and between fluorescent dyes in two-color experiments in spotted DNA microarrays. CONCLUSIONS: Array-A-Lizer allows the expedient determination of the quality of multiple DNA microarray experiments allowing for a rapid initial screening of results before progressing to further data analysis. Array-A-Lizer is directed towards speed and ease-of-use allowing both the expert and non-expert microarray researcher to rapidly assess the quality of multiple microarray hybridizations. Array-A-Lizer is available from the Internet as both source code and as a binary installation package. BioMed Central 2004-02-09 /pmc/articles/PMC356907/ /pubmed/15018654 http://dx.doi.org/10.1186/1471-2105-5-12 Text en Copyright © 2004 Petri et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
spellingShingle Software
Petri, Andreas
Fleckner, Jan
Matthiessen, Mads Wichmann
Array-A-Lizer: A serial DNA microarray quality analyzer
title Array-A-Lizer: A serial DNA microarray quality analyzer
title_full Array-A-Lizer: A serial DNA microarray quality analyzer
title_fullStr Array-A-Lizer: A serial DNA microarray quality analyzer
title_full_unstemmed Array-A-Lizer: A serial DNA microarray quality analyzer
title_short Array-A-Lizer: A serial DNA microarray quality analyzer
title_sort array-a-lizer: a serial dna microarray quality analyzer
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC356907/
https://www.ncbi.nlm.nih.gov/pubmed/15018654
http://dx.doi.org/10.1186/1471-2105-5-12
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