(2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone

In the title compound, C(18)H(18)F(2)N(2)O(3)S, the piperazine ring adopts a chair conformation. The dihedral angle between the sulfonyl-bound benzene ring and the best fit plane throught the six non-H atoms of the piperazine ring is 69.4 (2)°, while those between the fluoro­benzene and sulfonyl rin...

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Autores principales: Sreenivasa, S., ManojKumar, K. E., Suchetan, P. A., Tonannavar, J., Chavan, Yashshwita, Palakshamurthy, B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569247/
https://www.ncbi.nlm.nih.gov/pubmed/23424470
http://dx.doi.org/10.1107/S1600536812051690
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author Sreenivasa, S.
ManojKumar, K. E.
Suchetan, P. A.
Tonannavar, J.
Chavan, Yashshwita
Palakshamurthy, B. S.
author_facet Sreenivasa, S.
ManojKumar, K. E.
Suchetan, P. A.
Tonannavar, J.
Chavan, Yashshwita
Palakshamurthy, B. S.
author_sort Sreenivasa, S.
collection PubMed
description In the title compound, C(18)H(18)F(2)N(2)O(3)S, the piperazine ring adopts a chair conformation. The dihedral angle between the sulfonyl-bound benzene ring and the best fit plane throught the six non-H atoms of the piperazine ring is 69.4 (2)°, while those between the fluoro­benzene and sulfonyl rings and the fluoro­benzene and piperazine rings are 30.97 (2) and 75.98 (2)°, respectively. In the crystal, mol­ecules are connected to form a tetra­meric unit through C—H⋯O hydrogen bonds. The structure is further stabilized by weak inter­molecular C—H⋯F inter­actions, generating C(8) and C(7) chains running along [100].
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spelling pubmed-35692472013-02-19 (2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone Sreenivasa, S. ManojKumar, K. E. Suchetan, P. A. Tonannavar, J. Chavan, Yashshwita Palakshamurthy, B. S. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(18)F(2)N(2)O(3)S, the piperazine ring adopts a chair conformation. The dihedral angle between the sulfonyl-bound benzene ring and the best fit plane throught the six non-H atoms of the piperazine ring is 69.4 (2)°, while those between the fluoro­benzene and sulfonyl rings and the fluoro­benzene and piperazine rings are 30.97 (2) and 75.98 (2)°, respectively. In the crystal, mol­ecules are connected to form a tetra­meric unit through C—H⋯O hydrogen bonds. The structure is further stabilized by weak inter­molecular C—H⋯F inter­actions, generating C(8) and C(7) chains running along [100]. International Union of Crystallography 2013-01-04 /pmc/articles/PMC3569247/ /pubmed/23424470 http://dx.doi.org/10.1107/S1600536812051690 Text en © Sreenivasa et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sreenivasa, S.
ManojKumar, K. E.
Suchetan, P. A.
Tonannavar, J.
Chavan, Yashshwita
Palakshamurthy, B. S.
(2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone
title (2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone
title_full (2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone
title_fullStr (2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone
title_full_unstemmed (2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone
title_short (2,3-Difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone
title_sort (2,3-difluoro­phen­yl)(4-tosyl­piperazin-1-yl)methanone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569247/
https://www.ncbi.nlm.nih.gov/pubmed/23424470
http://dx.doi.org/10.1107/S1600536812051690
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