4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine

The title compound, C(10)H(16)N(4), crystalizes with two mol­ecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in one of the mol­ecules are disordered over two sets of s...

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Autores principales: Sreenivasa, S., ManojKumar, K. E., Srinivasan, T., Suchetan, P. A., Palakshamurthy, B. S., Velumurgan, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569258/
https://www.ncbi.nlm.nih.gov/pubmed/23424481
http://dx.doi.org/10.1107/S1600536812050982
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author Sreenivasa, S.
ManojKumar, K. E.
Srinivasan, T.
Suchetan, P. A.
Palakshamurthy, B. S.
Velumurgan, D.
author_facet Sreenivasa, S.
ManojKumar, K. E.
Srinivasan, T.
Suchetan, P. A.
Palakshamurthy, B. S.
Velumurgan, D.
author_sort Sreenivasa, S.
collection PubMed
description The title compound, C(10)H(16)N(4), crystalizes with two mol­ecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in one of the mol­ecules are disordered over two sets of sites with occupancy factors 0.508 (11):0.492 (11). In the crystal, the A mol­ecules are linked to one another through N—H⋯N hydrogen bonds, generating R (2) (2)(8) ring patterns and forming inversion dimers. These dimers are further connected on either side to a B molecule through pairs of N—H⋯N hydrogen bonds, resulting in a tetra­meric unit.
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spelling pubmed-35692582013-02-19 4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine Sreenivasa, S. ManojKumar, K. E. Srinivasan, T. Suchetan, P. A. Palakshamurthy, B. S. Velumurgan, D. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(10)H(16)N(4), crystalizes with two mol­ecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in one of the mol­ecules are disordered over two sets of sites with occupancy factors 0.508 (11):0.492 (11). In the crystal, the A mol­ecules are linked to one another through N—H⋯N hydrogen bonds, generating R (2) (2)(8) ring patterns and forming inversion dimers. These dimers are further connected on either side to a B molecule through pairs of N—H⋯N hydrogen bonds, resulting in a tetra­meric unit. International Union of Crystallography 2013-01-09 /pmc/articles/PMC3569258/ /pubmed/23424481 http://dx.doi.org/10.1107/S1600536812050982 Text en © Sreenivasa et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sreenivasa, S.
ManojKumar, K. E.
Srinivasan, T.
Suchetan, P. A.
Palakshamurthy, B. S.
Velumurgan, D.
4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine
title 4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine
title_full 4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine
title_fullStr 4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine
title_full_unstemmed 4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine
title_short 4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine
title_sort 4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569258/
https://www.ncbi.nlm.nih.gov/pubmed/23424481
http://dx.doi.org/10.1107/S1600536812050982
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AT velumurgand 4methyl6piperidin1ylpyrimidin2amine

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