Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis

The Bacillus anthracis Carbosap genome, which includes the pXO1 and pXO2 plasmids, has been shown to encode the major B. anthracis virulence factors, yet this strain’s attenuation has not yet been explained. Here we report the draft genome sequence of this strain, and a comparison to fully virulent...

Descripción completa

Detalles Bibliográficos
Autores principales: Harrington, Robin, Ondov, Brian D., Radune, Diana, Friss, Mary Beth, Klubnik, Joy, Diviak, Lynn, Hnath, Jonathan, Cendrowski, Stephen R., Blank, Thomas E., Karaolis, David, Friedlander, Arthur M., Burans, James P., Rosovitz, M. J., Treangen, Todd, Phillippy, Adam M., Bergman, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2013
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569327/
https://www.ncbi.nlm.nih.gov/pubmed/23405332
http://dx.doi.org/10.1128/genomeA.00067-12
_version_ 1782258880414220288
author Harrington, Robin
Ondov, Brian D.
Radune, Diana
Friss, Mary Beth
Klubnik, Joy
Diviak, Lynn
Hnath, Jonathan
Cendrowski, Stephen R.
Blank, Thomas E.
Karaolis, David
Friedlander, Arthur M.
Burans, James P.
Rosovitz, M. J.
Treangen, Todd
Phillippy, Adam M.
Bergman, Nicholas H.
author_facet Harrington, Robin
Ondov, Brian D.
Radune, Diana
Friss, Mary Beth
Klubnik, Joy
Diviak, Lynn
Hnath, Jonathan
Cendrowski, Stephen R.
Blank, Thomas E.
Karaolis, David
Friedlander, Arthur M.
Burans, James P.
Rosovitz, M. J.
Treangen, Todd
Phillippy, Adam M.
Bergman, Nicholas H.
author_sort Harrington, Robin
collection PubMed
description The Bacillus anthracis Carbosap genome, which includes the pXO1 and pXO2 plasmids, has been shown to encode the major B. anthracis virulence factors, yet this strain’s attenuation has not yet been explained. Here we report the draft genome sequence of this strain, and a comparison to fully virulent B. anthracis.
format Online
Article
Text
id pubmed-3569327
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher American Society for Microbiology
record_format MEDLINE/PubMed
spelling pubmed-35693272013-02-12 Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis Harrington, Robin Ondov, Brian D. Radune, Diana Friss, Mary Beth Klubnik, Joy Diviak, Lynn Hnath, Jonathan Cendrowski, Stephen R. Blank, Thomas E. Karaolis, David Friedlander, Arthur M. Burans, James P. Rosovitz, M. J. Treangen, Todd Phillippy, Adam M. Bergman, Nicholas H. Genome Announc Prokaryotes The Bacillus anthracis Carbosap genome, which includes the pXO1 and pXO2 plasmids, has been shown to encode the major B. anthracis virulence factors, yet this strain’s attenuation has not yet been explained. Here we report the draft genome sequence of this strain, and a comparison to fully virulent B. anthracis. American Society for Microbiology 2013-01-15 /pmc/articles/PMC3569327/ /pubmed/23405332 http://dx.doi.org/10.1128/genomeA.00067-12 Text en Copyright © 2013 Harrington et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Harrington, Robin
Ondov, Brian D.
Radune, Diana
Friss, Mary Beth
Klubnik, Joy
Diviak, Lynn
Hnath, Jonathan
Cendrowski, Stephen R.
Blank, Thomas E.
Karaolis, David
Friedlander, Arthur M.
Burans, James P.
Rosovitz, M. J.
Treangen, Todd
Phillippy, Adam M.
Bergman, Nicholas H.
Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis
title Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis
title_full Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis
title_fullStr Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis
title_full_unstemmed Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis
title_short Genome Sequence of the Attenuated Carbosap Vaccine Strain of Bacillus anthracis
title_sort genome sequence of the attenuated carbosap vaccine strain of bacillus anthracis
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569327/
https://www.ncbi.nlm.nih.gov/pubmed/23405332
http://dx.doi.org/10.1128/genomeA.00067-12
work_keys_str_mv AT harringtonrobin genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT ondovbriand genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT radunediana genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT frissmarybeth genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT klubnikjoy genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT diviaklynn genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT hnathjonathan genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT cendrowskistephenr genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT blankthomase genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT karaolisdavid genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT friedlanderarthurm genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT buransjamesp genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT rosovitzmj genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT treangentodd genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT phillippyadamm genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis
AT bergmannicholash genomesequenceoftheattenuatedcarbosapvaccinestrainofbacillusanthracis

Ejemplares similares