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Protochlamydia Induces Apoptosis of Human HEp-2 Cells through Mitochondrial Dysfunction Mediated by Chlamydial Protease-Like Activity Factor

Obligate amoebal endosymbiotic bacterium Protochlamydia with ancestral pathogenic chlamydial features evolved to survive within protist hosts, such as Acanthamoba, 0.7–1.4 billion years ago, but not within vertebrates including humans. This observation raises the possibility that interactions betwee...

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Detalles Bibliográficos
Autores principales: Matsuo, Junji, Nakamura, Shinji, Ito, Atsushi, Yamazaki, Tomohiro, Ishida, Kasumi, Hayashi, Yasuhiro, Yoshida, Mitsutaka, Takahashi, Kaori, Sekizuka, Tsuyoshi, Takeuchi, Fumihiko, Kuroda, Makoto, Nagai, Hiroki, Hayashida, Kyoko, Sugimoto, Chihiro, Yamaguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569409/
https://www.ncbi.nlm.nih.gov/pubmed/23409113
http://dx.doi.org/10.1371/journal.pone.0056005