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Protochlamydia Induces Apoptosis of Human HEp-2 Cells through Mitochondrial Dysfunction Mediated by Chlamydial Protease-Like Activity Factor
Obligate amoebal endosymbiotic bacterium Protochlamydia with ancestral pathogenic chlamydial features evolved to survive within protist hosts, such as Acanthamoba, 0.7–1.4 billion years ago, but not within vertebrates including humans. This observation raises the possibility that interactions betwee...
Autores principales: | Matsuo, Junji, Nakamura, Shinji, Ito, Atsushi, Yamazaki, Tomohiro, Ishida, Kasumi, Hayashi, Yasuhiro, Yoshida, Mitsutaka, Takahashi, Kaori, Sekizuka, Tsuyoshi, Takeuchi, Fumihiko, Kuroda, Makoto, Nagai, Hiroki, Hayashida, Kyoko, Sugimoto, Chihiro, Yamaguchi, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569409/ https://www.ncbi.nlm.nih.gov/pubmed/23409113 http://dx.doi.org/10.1371/journal.pone.0056005 |
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