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A Potential New Pathway for PD-L1 Costimulation of the CD8-T Cell Response to Listeria monocytogenes Infection

Programmed death ligand-1 (PD-L1) is an important negative regulator of T cell immune responses via interactions with PD-1 and CD80. However, PD-L1 can also act as a positive costimulator, but the relevant counterreceptor is not known. We analyzed the role of PD-L1 in CD8-T cell responses to infecti...

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Detalles Bibliográficos
Autores principales: Xu, Daqi, Fu, Han-Hsuan, Obar, Joshua J., Park, Jang-June, Tamada, Koji, Yagita, Hideo, Lefrançois, Leo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569435/
https://www.ncbi.nlm.nih.gov/pubmed/23409193
http://dx.doi.org/10.1371/journal.pone.0056539