CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells

CD40L has a well-established role in enhancing the immunostimulatory capacity of normal and malignant B cells, but a formulation suitable for clinical use has not been widely available. Like other TNF family members, in vivo and in vitro activity of CD40L requires a homotrimeric configuration, and g...

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Detalles Bibliográficos
Autores principales: Naito, Masayasu, Hainz, Ursula, Burkhardt, Ute E., Fu, Buyin, Ahove, Deborah, Stevenson, Kristen E., Rajasagi, Mohini, Zhu, Baogong, Alonso, Anselmo, Witten, Elizabeth, Matsuoka, Ken-ichi, Neuberg, Donna, Duke-Cohan, Jonathan S., Wu, Catherine J., Freeman, Gordon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569584/
https://www.ncbi.nlm.nih.gov/pubmed/22926059
http://dx.doi.org/10.1007/s00262-012-1331-4

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