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Impact of rtI233V mutation in hepatitis B virus polymerase protein and adefovir efficacy: Homology modeling and molecular docking studies

Adefovir is an adenosine analogue approved by the Food and Drug Administration for the treatment of chronic hepatitis B. Mutations occurring in the hepatitis B virus (HBV) reverse transcriptase (rt) domains are shown to confer resistance to antiviral drugs. The role of the rtI233V mutation and adefo...

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Detalles Bibliográficos
Autores principales:	Ismail, Ashrafali Mohamed, Sharma, Om Prakash, Kumar, Muthuvel Suresh, Kannangai, Rajesh, Abraham, Priya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2013
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569598/ https://www.ncbi.nlm.nih.gov/pubmed/23423477 http://dx.doi.org/10.6026/97320630009121

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