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Quantum combinatorial model of gene expression

We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We also hypothesize that states within the library may be linked via quantum tunneling. RNA polymerase then could scan these states and the system deco...

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Detalles Bibliográficos
Autores principales: Grover, Monendra, Grover, Ritu, Singh, Rakesh, Kumar, Rajesh, Kumar, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569601/
https://www.ncbi.nlm.nih.gov/pubmed/23422839
http://dx.doi.org/10.6026/97320630009141
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author Grover, Monendra
Grover, Ritu
Singh, Rakesh
Kumar, Rajesh
Kumar, Sundeep
author_facet Grover, Monendra
Grover, Ritu
Singh, Rakesh
Kumar, Rajesh
Kumar, Sundeep
author_sort Grover, Monendra
collection PubMed
description We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We also hypothesize that states within the library may be linked via quantum tunneling. RNA polymerase then could scan these states and the system decoheres to the “appropriate” state. Two ways of sustaining quantum coherence at relevant time scales could be possible, first, screening: the quantum system can be kept isolated from its decohering environment, second, the existence of decoherence free subspaces .We discuss the role of superconductivity in context of avoiding decoherence in context of our hypothesis.
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spelling pubmed-35696012013-02-19 Quantum combinatorial model of gene expression Grover, Monendra Grover, Ritu Singh, Rakesh Kumar, Rajesh Kumar, Sundeep Bioinformation Hypothesis We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We also hypothesize that states within the library may be linked via quantum tunneling. RNA polymerase then could scan these states and the system decoheres to the “appropriate” state. Two ways of sustaining quantum coherence at relevant time scales could be possible, first, screening: the quantum system can be kept isolated from its decohering environment, second, the existence of decoherence free subspaces .We discuss the role of superconductivity in context of avoiding decoherence in context of our hypothesis. Biomedical Informatics 2013-02-06 /pmc/articles/PMC3569601/ /pubmed/23422839 http://dx.doi.org/10.6026/97320630009141 Text en © 2013 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Hypothesis
Grover, Monendra
Grover, Ritu
Singh, Rakesh
Kumar, Rajesh
Kumar, Sundeep
Quantum combinatorial model of gene expression
title Quantum combinatorial model of gene expression
title_full Quantum combinatorial model of gene expression
title_fullStr Quantum combinatorial model of gene expression
title_full_unstemmed Quantum combinatorial model of gene expression
title_short Quantum combinatorial model of gene expression
title_sort quantum combinatorial model of gene expression
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569601/
https://www.ncbi.nlm.nih.gov/pubmed/23422839
http://dx.doi.org/10.6026/97320630009141
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