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Quantum combinatorial model of gene expression
We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We also hypothesize that states within the library may be linked via quantum tunneling. RNA polymerase then could scan these states and the system deco...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569601/ https://www.ncbi.nlm.nih.gov/pubmed/23422839 http://dx.doi.org/10.6026/97320630009141 |
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author | Grover, Monendra Grover, Ritu Singh, Rakesh Kumar, Rajesh Kumar, Sundeep |
author_facet | Grover, Monendra Grover, Ritu Singh, Rakesh Kumar, Rajesh Kumar, Sundeep |
author_sort | Grover, Monendra |
collection | PubMed |
description | We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We also hypothesize that states within the library may be linked via quantum tunneling. RNA polymerase then could scan these states and the system decoheres to the “appropriate” state. Two ways of sustaining quantum coherence at relevant time scales could be possible, first, screening: the quantum system can be kept isolated from its decohering environment, second, the existence of decoherence free subspaces .We discuss the role of superconductivity in context of avoiding decoherence in context of our hypothesis. |
format | Online Article Text |
id | pubmed-3569601 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Biomedical Informatics |
record_format | MEDLINE/PubMed |
spelling | pubmed-35696012013-02-19 Quantum combinatorial model of gene expression Grover, Monendra Grover, Ritu Singh, Rakesh Kumar, Rajesh Kumar, Sundeep Bioinformation Hypothesis We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We also hypothesize that states within the library may be linked via quantum tunneling. RNA polymerase then could scan these states and the system decoheres to the “appropriate” state. Two ways of sustaining quantum coherence at relevant time scales could be possible, first, screening: the quantum system can be kept isolated from its decohering environment, second, the existence of decoherence free subspaces .We discuss the role of superconductivity in context of avoiding decoherence in context of our hypothesis. Biomedical Informatics 2013-02-06 /pmc/articles/PMC3569601/ /pubmed/23422839 http://dx.doi.org/10.6026/97320630009141 Text en © 2013 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. |
spellingShingle | Hypothesis Grover, Monendra Grover, Ritu Singh, Rakesh Kumar, Rajesh Kumar, Sundeep Quantum combinatorial model of gene expression |
title | Quantum combinatorial model of gene expression |
title_full | Quantum combinatorial model of gene expression |
title_fullStr | Quantum combinatorial model of gene expression |
title_full_unstemmed | Quantum combinatorial model of gene expression |
title_short | Quantum combinatorial model of gene expression |
title_sort | quantum combinatorial model of gene expression |
topic | Hypothesis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569601/ https://www.ncbi.nlm.nih.gov/pubmed/23422839 http://dx.doi.org/10.6026/97320630009141 |
work_keys_str_mv | AT grovermonendra quantumcombinatorialmodelofgeneexpression AT groverritu quantumcombinatorialmodelofgeneexpression AT singhrakesh quantumcombinatorialmodelofgeneexpression AT kumarrajesh quantumcombinatorialmodelofgeneexpression AT kumarsundeep quantumcombinatorialmodelofgeneexpression |