The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

Immunoglobulins, antigens and complement can assemble to form immune complexes (IC). ICs can be detrimental as they propagate inflammation in autoimmune diseases. Like ICs, submicron extracellular vesicles termed microparticles (MP) are present in the synovial fluid from patients affected with autoi...

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Detalles Bibliográficos
Autores principales: Cloutier, Nathalie, Tan, Sisareuth, Boudreau, Luc H, Cramb, Catriona, Subbaiah, Roopashree, Lahey, Lauren, Albert, Alexandra, Shnayder, Ruslan, Gobezie, Reuben, Nigrovic, Peter A, Farndale, Richard W, Robinson, William H, Brisson, Alain, Lee, David M, Boilard, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569640/
https://www.ncbi.nlm.nih.gov/pubmed/23165896
http://dx.doi.org/10.1002/emmm.201201846

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