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4-[Bis(4-fluoro­phen­yl)meth­yl]-1-[(2E)-3-phenyl­prop-2-en-1-yl]piperazin-1-ium 3-carb­oxy­propano­ate

In the title salt, C(26)H(27)F(2)N(2) (+)·C(4)H(5)O(4) (−), the piperazine N atom bearing the vinylic substituent is protonated. The piperazine ring adopts a chair conformation. In ther crystal, the succinate monoanions are connected via short O—H⋯O hydrogen bonds between the carb­oxy­lic acid and c...

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Detalles Bibliográficos
Autores principales: Kavitha, Channappa N., Yathirajan, Hemmige S., Narayana, Badiadka, Gerber, Thomas, van Brecht, Benjamin, Betz, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569791/
https://www.ncbi.nlm.nih.gov/pubmed/23424537
http://dx.doi.org/10.1107/S1600536813000706
Descripción
Sumario:In the title salt, C(26)H(27)F(2)N(2) (+)·C(4)H(5)O(4) (−), the piperazine N atom bearing the vinylic substituent is protonated. The piperazine ring adopts a chair conformation. In ther crystal, the succinate monoanions are connected via short O—H⋯O hydrogen bonds between the carb­oxy­lic acid and carboxyl­ate groups into undulating chains extending along [001] and the flunarizinium monocations are attached to these chains via N(+)—H⋯O(−) hydrogen bonds. C—H⋯O inter­actions connect these chains into a three-dimensional network. The shortest centroid–centroid distance of 3.7256 (10) Å was found between one of the fluorinated benzene rings and the non-fluorinated phenyl ring in the neighbouring mol­ecule related by a glide plane.