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(4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid
The asymmetric unit of the title compound, C(17)H(15)NO(4), contains two independent molecules with similar geometric parameters. In both molecules, the conformation of the cyclohexene ring is half-chair, while the pyrrolidinone ring adopts an envelope conformation with the γ-carbon atom of the α...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569801/ https://www.ncbi.nlm.nih.gov/pubmed/23424547 http://dx.doi.org/10.1107/S160053681300144X |
| _version_ | 1782258965924544512 |
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| author | Horak, Yuriy I. Lytvyn, Roman Z. Zubkov, Fedor I. Nikitina, Eugeniya V. Homza, Yuriy V. Lis, Tadeusz Kinzhybalo, Vasyl Obushak, Mykola D. |
| author_facet | Horak, Yuriy I. Lytvyn, Roman Z. Zubkov, Fedor I. Nikitina, Eugeniya V. Homza, Yuriy V. Lis, Tadeusz Kinzhybalo, Vasyl Obushak, Mykola D. |
| author_sort | Horak, Yuriy I. |
| collection | PubMed |
| description | The asymmetric unit of the title compound, C(17)H(15)NO(4), contains two independent molecules with similar geometric parameters. In both molecules, the conformation of the cyclohexene ring is half-chair, while the pyrrolidinone ring adopts an envelope conformation with the γ-carbon atom of the α-pyrrolidinone ring as the flap. In the crystal, O—H⋯O hydrogen bonds between the carboxylic and carbonyl groups link alternate independent molecules into chains propagating in the b-axis direction. The crystal packing also features weak C—H⋯π interactions. |
| format | Online Article Text |
| id | pubmed-3569801 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-35698012013-02-19 (4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid Horak, Yuriy I. Lytvyn, Roman Z. Zubkov, Fedor I. Nikitina, Eugeniya V. Homza, Yuriy V. Lis, Tadeusz Kinzhybalo, Vasyl Obushak, Mykola D. Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(17)H(15)NO(4), contains two independent molecules with similar geometric parameters. In both molecules, the conformation of the cyclohexene ring is half-chair, while the pyrrolidinone ring adopts an envelope conformation with the γ-carbon atom of the α-pyrrolidinone ring as the flap. In the crystal, O—H⋯O hydrogen bonds between the carboxylic and carbonyl groups link alternate independent molecules into chains propagating in the b-axis direction. The crystal packing also features weak C—H⋯π interactions. International Union of Crystallography 2013-01-23 /pmc/articles/PMC3569801/ /pubmed/23424547 http://dx.doi.org/10.1107/S160053681300144X Text en © Horak et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Horak, Yuriy I. Lytvyn, Roman Z. Zubkov, Fedor I. Nikitina, Eugeniya V. Homza, Yuriy V. Lis, Tadeusz Kinzhybalo, Vasyl Obushak, Mykola D. (4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid |
| title | (4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid |
| title_full | (4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid |
| title_fullStr | (4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid |
| title_full_unstemmed | (4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid |
| title_short | (4R*,4aR*,7aS*)-5-Oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4H-furo[2,3-f]isoindole-4-carboxylic acid |
| title_sort | (4r*,4ar*,7as*)-5-oxo-6-phenyl-4a,5,6,7,7a,8-hexahydro-4h-furo[2,3-f]isoindole-4-carboxylic acid |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569801/ https://www.ncbi.nlm.nih.gov/pubmed/23424547 http://dx.doi.org/10.1107/S160053681300144X |
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