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Ethyl 4-hy­droxy-1-methyl-5-oxo-2-phenyl­pyrrolidine-3-carboxyl­ate 1.25-hydrate

The asymmetric unit of the title compound, C(14)H(17)NO(4)·1.25H(2)O, consists of four substituted pyrrolidone mol­ecules (two pairs of enanti­omers) and five water mol­ecules. The five-membered rings each have an envelope conformation, with the C atom bonded to the ester group as the flap. The mean...

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Detalles Bibliográficos
Autores principales: Mansor, Nurul Shulehaf, Mohammat, Mohd Fazli, Shaameri, Zurina, Khaledi, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569816/
https://www.ncbi.nlm.nih.gov/pubmed/23424562
http://dx.doi.org/10.1107/S1600536813001943
Descripción
Sumario:The asymmetric unit of the title compound, C(14)H(17)NO(4)·1.25H(2)O, consists of four substituted pyrrolidone mol­ecules (two pairs of enanti­omers) and five water mol­ecules. The five-membered rings each have an envelope conformation, with the C atom bonded to the ester group as the flap. The mean planes of the five-membered rings of the four pyrrolidone mol­ecules make dihedral angles of 60.87 (5), 64.45 (5), 62.03 (5) and 65.79 (5)° with respect to the phenyl rings. In the crystal, the pyrrolidone and water mol­ecules are connected through O—H⋯O hydrogen bonds, forming a layer parallel to the ab plane. The two-dimensional network is further stabilized by inter­molecular C—H⋯O hydrogen bonds.