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3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid
In the title compound, C(24)H(25)N(3)O(5), the ethoxy group is disordered over two orientations in a 0.853 (14):0.147 (14) ratio. The benzimadazole ring system (r.m.s. deviation = 0.016 Å) makes a dihedral angle of 35.47 (7)° with the attached benzene ring. The pyrrolidine ring adopts an envelope c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569823/ https://www.ncbi.nlm.nih.gov/pubmed/23424569 http://dx.doi.org/10.1107/S1600536813001116 |
| _version_ | 1782258971121287168 |
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| author | Yoon, Yeong Keng Ali, Mohamed Ashraf Tan, Soo Choon Rosli, Mohd Mustaqim Razak, Ibrahim Abdul |
| author_facet | Yoon, Yeong Keng Ali, Mohamed Ashraf Tan, Soo Choon Rosli, Mohd Mustaqim Razak, Ibrahim Abdul |
| author_sort | Yoon, Yeong Keng |
| collection | PubMed |
| description | In the title compound, C(24)H(25)N(3)O(5), the ethoxy group is disordered over two orientations in a 0.853 (14):0.147 (14) ratio. The benzimadazole ring system (r.m.s. deviation = 0.016 Å) makes a dihedral angle of 35.47 (7)° with the attached benzene ring. The pyrrolidine ring adopts an envelope conformation with a methylene C atom as the flap. In the crystal, inversion dimers linked by pairs of O—H⋯N hydrogen bonds generate R (2) (2)(16) loops. C—H⋯O interactions link the dimers into a three-dimensional network. |
| format | Online Article Text |
| id | pubmed-3569823 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-35698232013-02-19 3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid Yoon, Yeong Keng Ali, Mohamed Ashraf Tan, Soo Choon Rosli, Mohd Mustaqim Razak, Ibrahim Abdul Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(25)N(3)O(5), the ethoxy group is disordered over two orientations in a 0.853 (14):0.147 (14) ratio. The benzimadazole ring system (r.m.s. deviation = 0.016 Å) makes a dihedral angle of 35.47 (7)° with the attached benzene ring. The pyrrolidine ring adopts an envelope conformation with a methylene C atom as the flap. In the crystal, inversion dimers linked by pairs of O—H⋯N hydrogen bonds generate R (2) (2)(16) loops. C—H⋯O interactions link the dimers into a three-dimensional network. International Union of Crystallography 2013-01-31 /pmc/articles/PMC3569823/ /pubmed/23424569 http://dx.doi.org/10.1107/S1600536813001116 Text en © Yoon et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Yoon, Yeong Keng Ali, Mohamed Ashraf Tan, Soo Choon Rosli, Mohd Mustaqim Razak, Ibrahim Abdul 3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid |
| title | 3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid |
| title_full | 3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid |
| title_fullStr | 3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid |
| title_full_unstemmed | 3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid |
| title_short | 3-{5-Ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazol-2-yl}benzoic acid |
| title_sort | 3-{5-ethoxycarbonyl-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1h-benzimidazol-2-yl}benzoic acid |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569823/ https://www.ncbi.nlm.nih.gov/pubmed/23424569 http://dx.doi.org/10.1107/S1600536813001116 |
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