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Recognition of lipid A variants by the TLR4-MD-2 receptor complex

Lipopolysaccharide (LPS) is a component of the outer membrane of almost all Gram-negative bacteria and consists of lipid A, core sugars, and O-antigen. LPS is recognized by Toll-like receptor 4 (TLR4) and MD-2 on host innate immune cells and can signal to activate the transcription factor NFκB, lead...

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Detalles Bibliográficos
Autores principales:	Maeshima, Nina, Fernandez, Rachel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569842/ https://www.ncbi.nlm.nih.gov/pubmed/23408095 http://dx.doi.org/10.3389/fcimb.2013.00003

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