Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways

Gene expression is regulated by DNA as well as histone modifications but the crosstalk and mechanistic link between these epigenetic signals are still poorly understood. Here we investigate the multi-domain protein Uhrf2 that is similar to Uhrf1, an essential cofactor of maintenance DNA methylation....

Descripción completa

Detalles Bibliográficos
Autores principales: Pichler, Garwin, Wolf, Patricia, Schmidt, Christine S, Meilinger, Daniela, Schneider, Katrin, Frauer, Carina, Fellinger, Karin, Rottach, Andrea, Leonhardt, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569875/
https://www.ncbi.nlm.nih.gov/pubmed/21598301
http://dx.doi.org/10.1002/jcb.23185

Ejemplares similares

Ejemplares similares