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Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome”
BACKGROUND: The neuroanatomic substrate of restless legs syndrome (RLS) is poorly understood, and the diagnosis is clinically made based upon subjective sensory symptoms, although a motor component is usually present. CASE REPORT: We report two cases of elderly patients with spinal pathology who wer...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Columbia University Libraries/Information Services
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569967/ https://www.ncbi.nlm.nih.gov/pubmed/23440307 |
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author | Ondo, William G. |
author_facet | Ondo, William G. |
author_sort | Ondo, William G. |
collection | PubMed |
description | BACKGROUND: The neuroanatomic substrate of restless legs syndrome (RLS) is poorly understood, and the diagnosis is clinically made based upon subjective sensory symptoms, although a motor component is usually present. CASE REPORT: We report two cases of elderly patients with spinal pathology who were referred by neurologists for myoclonus. Both had semi-rhythmic leg movements that partially improved while standing, but denied any urge to move. These movements improved dramatically with pramipexole, a dopamine agonist used for RLS. DISCUSSION: We propose that this “myoclonus” is actually the isolated stereotypic motor component of RLS. |
format | Online Article Text |
id | pubmed-3569967 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Columbia University Libraries/Information Services |
record_format | MEDLINE/PubMed |
spelling | pubmed-35699672013-02-25 Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome” Ondo, William G. Tremor Other Hyperkinet Mov (N Y) Case Report BACKGROUND: The neuroanatomic substrate of restless legs syndrome (RLS) is poorly understood, and the diagnosis is clinically made based upon subjective sensory symptoms, although a motor component is usually present. CASE REPORT: We report two cases of elderly patients with spinal pathology who were referred by neurologists for myoclonus. Both had semi-rhythmic leg movements that partially improved while standing, but denied any urge to move. These movements improved dramatically with pramipexole, a dopamine agonist used for RLS. DISCUSSION: We propose that this “myoclonus” is actually the isolated stereotypic motor component of RLS. Columbia University Libraries/Information Services 2012-03-20 /pmc/articles/PMC3569967/ /pubmed/23440307 Text en http://creativecommons.org/licenses/by-nc-nd/3.0/us/ This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommerical–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original author and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed. |
spellingShingle | Case Report Ondo, William G. Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome” |
title | Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome” |
title_full | Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome” |
title_fullStr | Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome” |
title_full_unstemmed | Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome” |
title_short | Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a “Pure Motor Restless Legs Syndrome” |
title_sort | movements mimicking myoclonus associated with spinal cord pathology: is this a “pure motor restless legs syndrome” |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569967/ https://www.ncbi.nlm.nih.gov/pubmed/23440307 |
work_keys_str_mv | AT ondowilliamg movementsmimickingmyoclonusassociatedwithspinalcordpathologyisthisapuremotorrestlesslegssyndrome |