CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation

CCN family protein 2 (CCN2), also known as connective tissue growth factor, is a secreting protein that modulates multiple cellular events. We previously demonstrated the metastasis-suppressive effect of CCN2 in lung cancer cells. In this study, we investigate the role of CCN2 in anoikis, a form of...

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Detalles Bibliográficos
Autores principales: Chang, C-C, Yang, M-H, Lin, B-R, Chen, S-T, Pan, S-H, Hsiao, M, Lai, T-C, Lin, S-K, Jeng, Y-M, Chu, C-Y, Chen, R-H, Yang, P-C, Eugene Chin, Y, Kuo, M-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569983/
https://www.ncbi.nlm.nih.gov/pubmed/23175185
http://dx.doi.org/10.1038/cdd.2012.136

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