Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor

BACKGROUND: Both hypothyroidism and Hashimoto's thyroiditis (HT) can rarely be associated with cerebellar ataxia. Severe essential tremor (ET) as well as bilateral thalamic deep brain stimulation (DBS) may lead to subtle cerebellar signs. CASE REPORT: We report a 74-year-old male with hypothyro...

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Autores principales: Shneyder, Natalya, Lyons, Mark K., Driver-dunckley, Erika, Evidente, Virgilio Gerald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Columbia University Libraries/Information Services 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569994/
https://www.ncbi.nlm.nih.gov/pubmed/23439792
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author Shneyder, Natalya
Lyons, Mark K.
Driver-dunckley, Erika
Evidente, Virgilio Gerald H.
author_facet Shneyder, Natalya
Lyons, Mark K.
Driver-dunckley, Erika
Evidente, Virgilio Gerald H.
author_sort Shneyder, Natalya
collection PubMed
description BACKGROUND: Both hypothyroidism and Hashimoto's thyroiditis (HT) can rarely be associated with cerebellar ataxia. Severe essential tremor (ET) as well as bilateral thalamic deep brain stimulation (DBS) may lead to subtle cerebellar signs. CASE REPORT: We report a 74-year-old male with hypothyroidism and a 20-year history of ET who developed cerebellar ataxia after bilateral thalamic DBS. Extensive workup revealed elevated thyroid stimulating hormone and thyroperoxidase antibody titers confirming the diagnosis of HT. DISCUSSION: Our case demonstrates multiple possible causes of cerebellar ataxia in a patient, including hypothyroidism, HT, chronic ET, and bilateral thalamic DBS. Counseling of patients may be appropriate when multiple risk factors for cerebellar ataxia coexist in one individual.
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spelling pubmed-35699942013-02-25 Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor Shneyder, Natalya Lyons, Mark K. Driver-dunckley, Erika Evidente, Virgilio Gerald H. Tremor Other Hyperkinet Mov (N Y) Case Report BACKGROUND: Both hypothyroidism and Hashimoto's thyroiditis (HT) can rarely be associated with cerebellar ataxia. Severe essential tremor (ET) as well as bilateral thalamic deep brain stimulation (DBS) may lead to subtle cerebellar signs. CASE REPORT: We report a 74-year-old male with hypothyroidism and a 20-year history of ET who developed cerebellar ataxia after bilateral thalamic DBS. Extensive workup revealed elevated thyroid stimulating hormone and thyroperoxidase antibody titers confirming the diagnosis of HT. DISCUSSION: Our case demonstrates multiple possible causes of cerebellar ataxia in a patient, including hypothyroidism, HT, chronic ET, and bilateral thalamic DBS. Counseling of patients may be appropriate when multiple risk factors for cerebellar ataxia coexist in one individual. Columbia University Libraries/Information Services 2012-03-22 /pmc/articles/PMC3569994/ /pubmed/23439792 Text en http://creativecommons.org/licenses/by-nc-nd/3.0/us/ This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommerical–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original author and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed.
spellingShingle Case Report
Shneyder, Natalya
Lyons, Mark K.
Driver-dunckley, Erika
Evidente, Virgilio Gerald H.
Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor
title Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor
title_full Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor
title_fullStr Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor
title_full_unstemmed Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor
title_short Cerebellar Ataxia from Multiple Potential Causes: Hypothyroidism, Hashimoto's Thyroiditis, Thalamic Stimulation, and Essential Tremor
title_sort cerebellar ataxia from multiple potential causes: hypothyroidism, hashimoto's thyroiditis, thalamic stimulation, and essential tremor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569994/
https://www.ncbi.nlm.nih.gov/pubmed/23439792
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