T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire

Activation induces extensive changes in the gene expression program of naive CD4(+) T cells, promoting their differentiation into helper T cells that coordinate immune responses. MicroRNAs (miRNAs) play a critical role in this process, and miRNA expression also changes dramatically during T cell dif...

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Detalles Bibliográficos
Autores principales: Bronevetsky, Yelena, Villarino, Alejandro V., Eisley, Christopher J., Barbeau, Rebecca, Barczak, Andrea J., Heinz, Gitta A., Kremmer, Elisabeth, Heissmeyer, Vigo, McManus, Michael T., Erle, David J., Rao, Anjana, Ansel, K. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570096/
https://www.ncbi.nlm.nih.gov/pubmed/23382546
http://dx.doi.org/10.1084/jem.20111717

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