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Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells

Thymus-derived (natural) CD4(+) FoxP3(+) regulatory T cells (nT reg cells) are required for immune homeostasis and self-tolerance, but must be stringently controlled to permit expansion of protective immunity. Previous findings linking signals transmitted through T cell–expressed C5a receptor (C5aR)...

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Detalles Bibliográficos
Autores principales:	Kwan, Wing-hong, van der Touw, William, Paz-Artal, Estela, Li, Ming O., Heeger, Peter S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570105/ https://www.ncbi.nlm.nih.gov/pubmed/23382542 http://dx.doi.org/10.1084/jem.20121525

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