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Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells
Thymus-derived (natural) CD4(+) FoxP3(+) regulatory T cells (nT reg cells) are required for immune homeostasis and self-tolerance, but must be stringently controlled to permit expansion of protective immunity. Previous findings linking signals transmitted through T cell–expressed C5a receptor (C5aR)...
Autores principales: | Kwan, Wing-hong, van der Touw, William, Paz-Artal, Estela, Li, Ming O., Heeger, Peter S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570105/ https://www.ncbi.nlm.nih.gov/pubmed/23382542 http://dx.doi.org/10.1084/jem.20121525 |
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