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Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels

During its life cycle, Leishmania undergoes extreme environmental changes, alternating between insect vectors and vertebrate hosts. Elevated temperature and decreased pH, conditions encountered after macrophage invasion, can induce axenic differentiation of avirulent promastigotes into virulent amas...

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Detalles Bibliográficos
Autores principales: Mittra, Bidyottam, Cortez, Mauro, Haydock, Andrew, Ramasamy, Gowthaman, Myler, Peter J., Andrews, Norma W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570109/
https://www.ncbi.nlm.nih.gov/pubmed/23382545
http://dx.doi.org/10.1084/jem.20121368

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