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Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels
During its life cycle, Leishmania undergoes extreme environmental changes, alternating between insect vectors and vertebrate hosts. Elevated temperature and decreased pH, conditions encountered after macrophage invasion, can induce axenic differentiation of avirulent promastigotes into virulent amas...
Autores principales: | Mittra, Bidyottam, Cortez, Mauro, Haydock, Andrew, Ramasamy, Gowthaman, Myler, Peter J., Andrews, Norma W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570109/ https://www.ncbi.nlm.nih.gov/pubmed/23382545 http://dx.doi.org/10.1084/jem.20121368 |
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