Cargando…

Targeting the T-cell membrane type-1 matrix metalloproteinase-CD44 axis in a transferred type 1 diabetes model in NOD mice

This study tested the hypothesis that membrane-tethered type-1 matrix metalloproteinase (MT1-MMP)-induced proteolysis of T cell CD44 is important for defining the migration and function of autoreactive T cells, including diabetogenic, insulin-specific and K(d)-restricted IS-CD8(+) cells. To confirm...

Descripción completa

Detalles Bibliográficos
Autores principales:	SAVINOV, ALEXEI Y., STRONGIN, ALEX Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570120/ https://www.ncbi.nlm.nih.gov/pubmed/23403478 http://dx.doi.org/10.3892/etm.2012.821

Ejemplares similares

Membrane Localization of Membrane Type 1 Matrix Metalloproteinase by CD44 Regulates the Activation of Pro-Matrix Metalloproteinase 9 in Osteoclasts
por: Chellaiah, Meenakshi A., et al.
Publicado: (2013)

Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration
por: Kajita, Masahiro, et al.
Publicado: (2001)

Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis
por: Remacle, Albert G, et al.
Publicado: (2016)

Matrix Metalloproteinase Proteolysis of the Myelin Basic Protein Isoforms Is a Source of Immunogenic Peptides in Autoimmune Multiple Sclerosis
por: Shiryaev, Sergey A., et al.
Publicado: (2009)

Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma
por: Kikuchi, R, et al.
Publicado: (2000)

Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissuenhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase
por: Collins, H M, et al.
Publicado: (2001)

Significance of Membrane Type 1 Matrix Metalloproteinase Expression in Breast Cancer
por: Ishigaki, Shinsuke, et al.
Publicado: (1999)

The Role of Membrane-Type 1 Matrix Metalloproteinase–Substrate Interactions in Pathogenesis
por: Lee, Hyun, et al.
Publicado: (2023)

Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression.
por: Hur, J. H., et al.
Publicado: (2000)

Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes
por: Xue, Song, et al.
Publicado: (2015)

Coordinated elevation of membrane type 1-matrix metalloproteinase and matrix metalloproteinase-2 expression in rat uterus during postpartum involution
por: Manase, Kengo, et al.
Publicado: (2006)

Matrix metalloproteinases in subjects with type 1 diabetes
por: Gharagozlian, Sedegheh, et al.
Publicado: (2009)

Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity
por: Cerofolini, Linda, et al.
Publicado: (2016)

Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression
por: Nyalendo, Carine, et al.
Publicado: (2009)

Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis
por: Sathyamoorthy, Tarangini, et al.
Publicado: (2015)

Membrane Type 1–Matrix Metalloproteinase/Akt Signaling Axis Modulates TNF-α-Induced Procoagulant Activity and Apoptosis in Endothelial Cells
por: Ohkawara, Hiroshi, et al.
Publicado: (2014)

Inhibition of matrix metalloproteinases by HIV-1 integrase strand transfer inhibitors
por: Foster, Emma G., et al.
Publicado: (2023)

Shedding of Membrane Type 1 Matrix Metalloproteinase in a Human Breast Carcinoma Cell Line
por: Harayama, Takeshi, et al.
Publicado: (1999)

Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism
por: Attur, Mukundan, et al.
Publicado: (2020)

Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis
por: Alabi, Adekunle, et al.
Publicado: (2021)

Membrane-type I matrix metalloproteinase (MT1-MMP), lipid metabolism, and therapeutic implications
por: Xia, Xiao-Dan, et al.
Publicado: (2021)

Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate
por: Nandadasa, Sumeda, et al.
Publicado: (2023)

High-molecular-weight hyaluronic acid attenuated matrix metalloproteinase-1 and -3 expression via CD44 in tendinopathy
por: Wu, Po-Ting, et al.
Publicado: (2017)

Impaired Expression of Membrane Type-2 and Type-3 Matrix Metalloproteinases in Endometriosis but Not in Adenomyosis
por: Maoga, Jane B., et al.
Publicado: (2022)

A Humanized Leucine Zipper-TRAIL Hybrid Induces Apoptosis of Tumors both In Vitro and In Vivo
por: Rozanov, Dmitri, et al.
Publicado: (2015)

A Membrane-Type-1 Matrix Metalloproteinase (MT1-MMP) – Discoidin Domain Receptor 1 Axis Regulates Collagen-Induced Apoptosis in Breast Cancer Cells
por: Assent, Delphine, et al.
Publicado: (2015)

Regulation of Cell Invasion and Morphogenesis in a Three-Dimensional Type I Collagen Matrix by Membrane-Type Matrix Metalloproteinases 1, 2, and 3
por: Hotary, Kevin, et al.
Publicado: (2000)

mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization
por: Kim, Daehwan, et al.
Publicado: (2016)

Dynamic Expression of Membrane Type 1-Matrix Metalloproteinase (Mt1-mmp/Mmp14) in the Mouse Embryo
por: Muñoz-Sáez, Emma, et al.
Publicado: (2021)

Expression of Matrix Metalloproteinases during Rat Skin Wound Healing: Evidence that Membrane Type-1 Matrix Metalloproteinase Is a Stromal Activator of Pro-Gelatinase A
por: Okada, Akiko, et al.
Publicado: (1997)

Membrane-type 1 matrix metalloproteinase-mediated progelatinase A activation in non-tumorigenic and tumorigenic humaneratinocytes
por: Baumann, P, et al.
Publicado: (2000)

The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain: CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTIONS
por: Tochowicz, Anna, et al.
Publicado: (2011)

Development of Radiolabeled Membrane Type-1 Matrix Metalloproteinase Activatable Cell Penetrating Peptide Imaging Probes
por: van Duijnhoven, Sander M. J., et al.
Publicado: (2015)

Integrated functions of membrane‐type 1 matrix metalloproteinase in regulating cancer malignancy: Beyond a proteinase
por: Sakamoto, Takeharu, et al.
Publicado: (2017)

Urine Levels of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Children with Type 1 Diabetes Mellitus
por: Yürük Yıldırım, Zeynep, et al.
Publicado: (2019)

Expression of CD44, Transforming Growth Factor-β, and Matrix Metalloproteinases in Women With Pelvic Organ Prolapse
por: Ying, Weiwei, et al.
Publicado: (2022)

Downregulation of membrane type-matrix metalloproteinases in the inflamed or injured central nervous system
por: Toft-Hansen, Henrik, et al.
Publicado: (2007)

Cell Migration through Extracellular Matrix: Membrane-Type Metalloproteinases Make the Way
por: Quaranta, Vito
Publicado: (2000)

LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells
por: Tapia, Tenekua, et al.
Publicado: (2011)

Membrane Type-1 Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases-2 RNA Levels Mimic Each Other during Xenopus laevis Metamorphosis
por: Walsh, Logan A., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_6btboku8j7fo8bqirpphsbjt2e