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Association between urinary 6β-hydroxycortisol/cortisol ratio and CYP3A5 genotypes in a normotensive population

Genetic polymorphism of genes involved in renal salt handling and arterial vessel tone is considered to be one of the causes of hypertension. Numerous reports suggest that cytochrome P4503A5 (CYP3A5) catalyzes 6β-hydroxylation of endogenous cortisol (CS), which is associated with sodium and water re...

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Detalles Bibliográficos
Autores principales:	RAIS, NAUSHAD, HUSSAIN, ARIF, CHAWLA, YOGESH KUMAR, KOHLI, KRISHAN K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570147/ https://www.ncbi.nlm.nih.gov/pubmed/23404385 http://dx.doi.org/10.3892/etm.2012.842

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