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Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments
Motivation: Cell populations are never truly homogeneous; individual cells exist in biochemical states that define functional differences between them. New technology based on microfluidic arrays combined with multiplexed quantitative polymerase chain reactions now enables high-throughput single-cel...
Autores principales: | McDavid, Andrew, Finak, Greg, Chattopadyay, Pratip K., Dominguez, Maria, Lamoreaux, Laurie, Ma, Steven S., Roederer, Mario, Gottardo, Raphael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570210/ https://www.ncbi.nlm.nih.gov/pubmed/23267174 http://dx.doi.org/10.1093/bioinformatics/bts714 |
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