The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs

Motivation: Fronto-temporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, also called motor neuron disease, MND) are severe neurodegenerative diseases that show considerable overlap at the clinical and cellular level. The most common single mutation in families with FTD or ALS has recently...

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Detalles Bibliográficos
Autores principales: Levine, Timothy P., Daniels, Rachel D., Gatta, Alberto T., Wong, Louise H., Hayes, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570213/
https://www.ncbi.nlm.nih.gov/pubmed/23329412
http://dx.doi.org/10.1093/bioinformatics/bts725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570213/
https://www.ncbi.nlm.nih.gov/pubmed/23329412
http://dx.doi.org/10.1093/bioinformatics/bts725

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