Development and validation of a HPLC-MS/MS method with electrospray ionization for quantitation of potassium oxonate in human plasma: Application to a pharmacokinetic study

A rapid, sensitive and specific HPLC-MS/MS method was developed and validated for the quantification of potassium oxonate (Oxo) in human plasma using [(13)C(2),(15)N(3)]-Oxo as an internal standard (IS). The target substance was separated from human plasma using the solid-phase extraction method. Ch...

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Detalles Bibliográficos
Autores principales: HAO, GUANGTAO, BAI, SHAOBO, LIANG, HAIXIA, LIANG, YUGUANG, QU, HENGYAN, GAO, HONGZHI, LI, YUANYUAN, ZHENG, ZHUANJIE, WANG, XIAOFANG, LIU, ZEYUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570248/
https://www.ncbi.nlm.nih.gov/pubmed/23407381
http://dx.doi.org/10.3892/etm.2013.908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570248/
https://www.ncbi.nlm.nih.gov/pubmed/23407381
http://dx.doi.org/10.3892/etm.2013.908

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