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Opposite effect of angiotensin receptor blockade on CXCL8 production and CXCR1/2 expression of angiotensin II-treated THP-1 monocytes

Interleukin-8 (IL-8) or CXCL8 is a potent chemotactic factor that is involved in atherogenesis. IL-8 mediates its pre-inflammatory effects through interaction with CXCR1 and CXCR2. In the present study, we investigated the effects of angiotensin II (Ang II) on IL-8 synthesis and CXCR1/CXCR2 expressi...

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Detalles Bibliográficos
Autores principales:	VOGIATZI, KONSTANTINA, APOSTOLAKIS, STAVROS, VLATA, ZAHARENIA, KRABOVITIS, ELIAS, SPANDIDOS, DEMETRIOS A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570251/ https://www.ncbi.nlm.nih.gov/pubmed/23407636 http://dx.doi.org/10.3892/etm.2013.909

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