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TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier

BACKGROUND: The TNF ligand family member TWEAK exists as membrane and soluble forms and is involved in the regulation of various human inflammatory pathologies, through binding to its main receptor, Fn14. We have shown that the soluble form of TWEAK has a pro-neuroinflammatory effect in an animal mo...

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Detalles Bibliográficos
Autores principales:	Stephan, Delphine, Sbai, Oualid, Wen, Jing, Couraud, Pierre-Olivier, Putterman, Chaim, Khrestchatisky, Michel, Desplat-Jégo, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570290/ https://www.ncbi.nlm.nih.gov/pubmed/23320797 http://dx.doi.org/10.1186/1742-2094-10-9

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