Importance of uncharged polar residues and proline in the proximal two-thirds (Pro(107)–Ser(128)) of the highly conserved region of mouse ileal Na(+)-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression

BACKGROUND: SLC10A2-mediated reabsorption of bile acids at the distal end of the ileum is the first step in enterohepatic circulation. Because bile acids act not only as detergents but also as signaling molecules in lipid metabolism and energy production, SLC10A2 is important as the key transporter...

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Detalles Bibliográficos
Autores principales: Saeki, Tohru, Sato, Kosuke, Ito, Shiho, Ikeda, Keisuke, Kanamoto, Ryuhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570448/
https://www.ncbi.nlm.nih.gov/pubmed/23374508
http://dx.doi.org/10.1186/1472-6793-13-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570448/
https://www.ncbi.nlm.nih.gov/pubmed/23374508
http://dx.doi.org/10.1186/1472-6793-13-4

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