Cargando…
Importance of uncharged polar residues and proline in the proximal two-thirds (Pro(107)–Ser(128)) of the highly conserved region of mouse ileal Na(+)-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression
BACKGROUND: SLC10A2-mediated reabsorption of bile acids at the distal end of the ileum is the first step in enterohepatic circulation. Because bile acids act not only as detergents but also as signaling molecules in lipid metabolism and energy production, SLC10A2 is important as the key transporter...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570448/ https://www.ncbi.nlm.nih.gov/pubmed/23374508 http://dx.doi.org/10.1186/1472-6793-13-4 |