Biochemical Characterization of Uracil Phosphoribosyltransferase from Mycobacterium tuberculosis

Uracil phosphoribosyltransferase (UPRT) catalyzes the conversion of uracil and 5-phosphoribosyl-α-1-pyrophosphate (PRPP) to uridine 5′-monophosphate (UMP) and pyrophosphate (PP(i)). UPRT plays an important role in the pyrimidine salvage pathway since UMP is a common precursor of all pyrimidine nucle...

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Detalles Bibliográficos
Autores principales: Villela, Anne Drumond, Ducati, Rodrigo Gay, Rosado, Leonardo Astolfi, Bloch, Carlos Junior, Prates, Maura Vianna, Gonçalves, Danieli Cristina, Ramos, Carlos Henrique Inacio, Basso, Luiz Augusto, Santos, Diogenes Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570474/
https://www.ncbi.nlm.nih.gov/pubmed/23424660
http://dx.doi.org/10.1371/journal.pone.0056445

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