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An Experimental Verification of the Predicted Effects of Promoter TATA-Box Polymorphisms Associated with Human Diseases on Interactions between the TATA Boxes and TATA-Binding Protein

Human genome sequencing has resulted in a great body of data, including a stunningly large number of single nucleotide polymorphisms (SNPs) with unknown phenotypic manifestations. Identification and comprehensive analysis of regulatory SNPs in human gene promoters will help quantify the effects of t...

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Detalles Bibliográficos
Autores principales:	Savinkova, Ludmila, Drachkova, Irina, Arshinova, Tatyana, Ponomarenko, Petr, Ponomarenko, Mikhail, Kolchanov, Nikolay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570547/ https://www.ncbi.nlm.nih.gov/pubmed/23424617 http://dx.doi.org/10.1371/journal.pone.0054626

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