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Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity
Toll-like receptors (TLRs) are traditionally associated with immune-mediated host defense. Here, we ascribe a novel extra-immune, hypothalamic-associated function to TLR2, a TLR-family member known to recognize lipid components, in the protection against obesity. We found that TLR2-deficient mice ex...
Autores principales: | Shechter, Ravid, London, Anat, Kuperman, Yael, Ronen, Ayal, Rolls, Asya, Chen, Alon, Schwartz, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570778/ https://www.ncbi.nlm.nih.gov/pubmed/23409245 http://dx.doi.org/10.1038/srep01254 |
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