New evidence for balancing selection at the HLA-G locus in South Amerindians

HLA-G is a non-classical HLA (Human Leukocyte Antigen) molecule characterized by limited tissue distribution under normal physiological conditions and low variability at both DNA and protein levels. Several studies suggest that HLA-G could play a role, as an immunoregulatory molecule, in situations...

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Detalles Bibliográficos
Autores principales: Veit, Tiago Degani, Cazarolli, Juciana, Salzano, Francisco Mauro, Schiengold, Marion, Chies, José Artur Bogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571432/
https://www.ncbi.nlm.nih.gov/pubmed/23412401

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