Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation

Selenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Such findings may relate to roles of Se in antioxidant protection, enhanced immune surveillance and modulation of cell proliferation. Elucidation...

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Detalles Bibliográficos
Autores principales: Zeng, Huawei, Cao, Jay J., Combs, Gerald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571640/
https://www.ncbi.nlm.nih.gov/pubmed/23306191
http://dx.doi.org/10.3390/nu5010097
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author Zeng, Huawei
Cao, Jay J.
Combs, Gerald F.
author_facet Zeng, Huawei
Cao, Jay J.
Combs, Gerald F.
author_sort Zeng, Huawei
collection PubMed
description Selenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Such findings may relate to roles of Se in antioxidant protection, enhanced immune surveillance and modulation of cell proliferation. Elucidation of the mechanisms by which Se supports these cellular processes can lead to a better understanding of the role of this nutrient in normal bone metabolism. This article reviews the current knowledge concerning the molecular functions of Se relevant to bone health.
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spelling pubmed-35716402013-02-19 Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation Zeng, Huawei Cao, Jay J. Combs, Gerald F. Nutrients Review Selenium (Se) is an essential trace element for humans and animals, and several findings suggest that dietary Se intake may be necessary for bone health. Such findings may relate to roles of Se in antioxidant protection, enhanced immune surveillance and modulation of cell proliferation. Elucidation of the mechanisms by which Se supports these cellular processes can lead to a better understanding of the role of this nutrient in normal bone metabolism. This article reviews the current knowledge concerning the molecular functions of Se relevant to bone health. MDPI 2013-01-10 /pmc/articles/PMC3571640/ /pubmed/23306191 http://dx.doi.org/10.3390/nu5010097 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Zeng, Huawei
Cao, Jay J.
Combs, Gerald F.
Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_full Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_fullStr Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_full_unstemmed Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_short Selenium in Bone Health: Roles in Antioxidant Protection and Cell Proliferation
title_sort selenium in bone health: roles in antioxidant protection and cell proliferation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571640/
https://www.ncbi.nlm.nih.gov/pubmed/23306191
http://dx.doi.org/10.3390/nu5010097
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