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αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion
The malignant brain cancer glioblastoma multiforme (GBM) displays invasive growth behaviors that are regulated by extracellular cues within the neural microenvironment. The adhesion and signaling pathways that drive GBM cell invasion remain largely uncharacterized. Here we use human GBM cell lines,...
Autores principales: | Reyes, Steve B., Narayanan, Anjana S., Lee, Hye Shin, Tchaicha, Jeremy H., Aldape, Kenneth D., Lang, Frederick F., Tolias, Kimberly F., McCarty, Joseph H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571870/ https://www.ncbi.nlm.nih.gov/pubmed/23283986 http://dx.doi.org/10.1091/mbc.E12-07-0521 |
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