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Mucosal transmissibility, disease induction and coreceptor switching of R5 SHIV(SF162P3N) molecular clones in rhesus macaques

BACKGROUND: Mucosally transmissible and pathogenic CCR5 (R5)-tropic simian-human immunodeficiency virus (SHIV) molecular clones are useful reagents to identity neutralization escape in HIV-1 vaccine experiments and to study the envelope evolutionary process and mechanistic basis for coreceptor switc...

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Detalles Bibliográficos
Autores principales: Ren, Wuze, Mumbauer, Alexandra, Zhuang, Ke, Harbison, Carole, Knight, Heather, Westmoreland, Susan, Gettie, Agegnehu, Blanchard, James, Cheng-Mayer, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571932/
https://www.ncbi.nlm.nih.gov/pubmed/23369442
http://dx.doi.org/10.1186/1742-4690-10-9