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Simple binary segmentation frameworks for identifying variation in DNA copy number
BACKGROUND: Variation in DNA copy number, due to gains and losses of chromosome segments, is common. A first step for analyzing DNA copy number data is to identify amplified or deleted regions in individuals. To locate such regions, we propose a circular binary segmentation procedure, which is based...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571941/ https://www.ncbi.nlm.nih.gov/pubmed/23107320 http://dx.doi.org/10.1186/1471-2105-13-277 |